BDBM441023 1-[2-Methyl-4-(2-oxo-3-aza-bicyclo[3.1.0]hex-3-ylmethyl)-benzyl]-1H-pyrazole-4-carboxylic acid ((R)-2-amino-6,7-dihydro-5H-[1]pyrindin-5-yl)-amide::US10640486, Example 69

SMILES Cc1cc(CN2CC3CC3C2=O)ccc1Cn1cc(cn1)C(=O)N[C@@H]1CCc2nc(N)ccc12

InChI Key InChIKey=NTEKAHYZVDAMTB-PSGUAHCZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 441023   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM441023(1-[2-Methyl-4-(2-oxo-3-aza-bicyclo[3.1.0]hex-3-ylm...)
Affinity DataIC50:  55nMAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Förster/Flouresence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent