BDBM441096 US10640495, Example I-258

SMILES COCCN1C[C@@H](NC(=O)Nc2c(C)c(-c3cnc4c(c3)[nH]c(=O)n4C)nn2-c2ccccc2)[C@H](c2cnc(F)c(F)c2)O1

InChI Key InChIKey=ZHSXDWNSYVEAAH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 441096   

TargetHigh affinity nerve growth factor receptor(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 441096BDBM441096(US10640495, Example I-258)
Affinity DataIC50: 0.480nMAssay Description:Seven point five μL per well of human TrkA (PV3144, Lifetechnologies, final concentration: 1 nmol/L) suspended in the assay buffer (100 mmol/L 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent