BDBM441716 (trans)-3-(5-(2-Chlorophenyl)indoline-1-carbonyl)-4-methylpyrrolidine-1-carbonitrile::US10640498, Example 13

SMILES C[C@@H]1CN(C[C@H]1C(=O)N1CCc2cc(ccc12)-c1ccccc1Cl)C#N

InChI Key InChIKey=GVKBOCNQLMSJGT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 441716   

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM441716((trans)-3-(5-(2-Chlorophenyl)indoline-1-carbonyl)-...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent