BDBM441872 US10647686, Example (19)::US10647686, Example 19

SMILES Cc1cnc(Nc2ccc(Cl)cc2)nc1NCCCN

InChI Key InChIKey=NMTICOSWEFXQCN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 441872   

TargetSerine/threonine-protein kinase 17A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM441872(US10647686, Example 19 | US10647686, Example (19))
Affinity DataIC50: 23nMAssay Description:To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetSerine/threonine-protein kinase 17A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM441872(US10647686, Example 19 | US10647686, Example (19))
Affinity DataIC50: 23nMAssay Description:To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetSerine/threonine-protein kinase 17A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM441872(US10647686, Example 19 | US10647686, Example (19))
Affinity DataIC50: 23nMAssay Description:To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetSerine/threonine-protein kinase 17B(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM441872(US10647686, Example 19 | US10647686, Example (19))
Affinity DataIC50: 710nMAssay Description:To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetSerine/threonine-protein kinase 17B(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM441872(US10647686, Example 19 | US10647686, Example (19))
Affinity DataIC50: 710nMAssay Description:To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent