BDBM441880 (2R)-1-(3-{3-[1-(4-Amino-3- methyl-1H-pyrazolo[3,4- d]pyrimidin-1-yl)ethyl]-5-eyloro-6- fluoro-2-methoxyphenyl}azetidin- 1-yl)propan-2-o12::US10646492, Example 69::US11433071, Example 68-1

SMILES COc1c(cc(Cl)c(F)c1C1CN(C[C@H](C)O)C1)[C@@H](C)n1nc(C)c2c(N)ncnc12

InChI Key InChIKey=QKFMWXFSQKPVRN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 441880   

LigandPNGBDBM441880((2R)-1-(3-{3-[1-(4-Amino-3- methyl-1H-pyrazolo[3,4...)
Affinity DataIC50: 10nMAssay Description:The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 uL. Inhibitors wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

LigandPNGBDBM441880((2R)-1-(3-{3-[1-(4-Amino-3- methyl-1H-pyrazolo[3,4...)
Affinity DataIC50: 10nMAssay Description:The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2022
Entry Details
US Patent