BDBM441960 US10647700, Compound 14

SMILES CCN(C(=O)C1CCCC1)c1cc(cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)-c1ccc(nc1)N1CCC(CC1)N(C)C

InChI Key InChIKey=RXCGZKRYSBAEDY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 441960   

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Tarapeutics Science

US Patent
LigandPNGBDBM441960(US10647700, Compound 14)
Affinity DataIC50: 75nMAssay Description:Enzymatic activity assay was conducted using EZH2(Y641F) TR-FRET assay KIT from Cisbio company on compounds that were shown to be active in primary s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent