BDBM442034 US10647708, Compound 23

SMILES OC(CCNC(=O)c1ccc2OC(F)(F)Oc2c1)CN1CCc2ccccc2C1

InChI Key InChIKey=DQXBVPITJGNOIS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 442034   

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandPNGBDBM442034(US10647708, Compound 23)
Affinity DataIC50: 1.69E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent