BDBM442044 US10647708, Compound 33

SMILES Cc1c(cnn1-c1ccccn1)C(=O)NCCC(O)CN1CCc2ccccc2C1

InChI Key InChIKey=IRIUGPUOHVBELH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 442044   

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandPNGBDBM442044(US10647708, Compound 33)
Affinity DataIC50: 7.45E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent