BDBM442706 US10647719, Example 1.17::[3-(2,2-dimethylpropanoylamino)-6-

SMILES Cc1ccc(NC(=O)C(C)(C)C)c(COC(=O)N2CC3=C(C2)CN(C3)C(=O)c2ccc(cc2F)S(N)(=O)=O)n1

InChI Key InChIKey=PMJWEXCPWYBIQC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 442706   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM442706(US10647719, Example 1.17 | [3-(2,2-dimethylpropano...)
Affinity DataIC50: 4nMAssay Description:Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetCarbonic anhydrase 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM442706(US10647719, Example 1.17 | [3-(2,2-dimethylpropano...)
Affinity DataIC50: 11nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent