BDBM442717 BDBM442732::US10647719, Example 1.28::[3-(2,2-dimethylpropanoylamino)-5-
SMILES CC(C)(C)C(=O)Nc1cc(cnc1COC(=O)N1CCC2=C(CCN(C2)C(=O)c2ccc(cc2F)S(N)(=O)=O)C1)C(F)(F)F
InChI Key InChIKey=YNNILJZFEPDRJM-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 442717
Affinity DataIC50: 1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair