BDBM442733 US10647719, Example 1.30::[5,6-dichloro-3-(2,2-

SMILES CC(C)(C)C(=O)Nc1cc(Cl)c(Cl)nc1COC(=O)N1CC2=C(C1)CN(C2)C(=O)c1ccc(cc1F)S(N)(=O)=O

InChI Key InChIKey=PNZPUSCEHHPUMB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 442733   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM442733(US10647719, Example 1.30 | [5,6-dichloro-3-(2,2-)
Affinity DataIC50: 4.20nMAssay Description:Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetCarbonic anhydrase 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM442733(US10647719, Example 1.30 | [5,6-dichloro-3-(2,2-)
Affinity DataIC50: 10nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent