BDBM442763 1,6-Dimethyl- N-{(1R)-1-[4- (trifluoromethyl)- phenyl]ethyl}-1H- pyrazolo[3,4-d]- pyrimidin-4-amine::US10647727, Example 21
SMILES C[C@@H](Nc1nc(C)nc2n(C)ncc12)c1ccc(cc1)C(F)(F)F
InChI Key InChIKey=XNZPHWRUVQOXID-SECBINFHSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 442763
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 140nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Affinity DataKi: 194nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair