BDBM442775 (R) N-(1-(3-Fluoro-4-(trifluoromethyl)phenyl)-2,2-dimethylpropyl)-7-methylimidazo[1,2-a]pyrimidin-5-amine::US10647727, Example 32

SMILES Cc1cc(N[C@@H](c2ccc(c(F)c2)C(F)(F)F)C(C)(C)C)n2ccnc2n1

InChI Key InChIKey=RDSOLVWNIYFUNX-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 442775   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM442775(US10647727, Example 32 | (R) N-(1-(3-Fluoro-4-(tri...)
Affinity DataKi:  51nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent