BDBM443373 7-(1,4-Dimethyl-1H- pyrazol-5-yl)-2-oxo- 1,4-dihydro-2H- spiro[pyrido[2,3- b]pyrazine-3,3'- pyrrolidine]-1'- carbonitrile::US10654853, Example 146

SMILES Cc1cnn(C)c1-c1cnc2NC3(CCN(C3)C#N)C(=O)Nc2c1

InChI Key InChIKey=VUVFSJXKHQAFBX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 443373   

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM443373(US10654853, Example 146 | 7-(1,4-Dimethyl-1H- pyra...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
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Date in BDB:
2/1/2021
Entry Details
US Patent