BDBM443415 US10654855, Example 38

SMILES Cc1c[nH]c2ncnc(N3CCC(N)(CC3)C(=O)N[C@@H](CC(C)(C)O)c3ccc(Cl)cc3)c12

InChI Key InChIKey=NRYYISGBALLFJD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 443415   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Astrazeneca

US Patent
LigandPNGBDBM443415(US10654855, Example 38)
Affinity DataIC50: 5.40nMAssay Description:For Echo dosing the solvent was 100% DMSO. A master plate was prepared with 40 ul of 10 mM stock from our Primary Liquid Store in quadrant 1 of a Lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2021
Entry Details
US Patent