BDBM44382 3-(2-Chloro-phenyl)-7-methyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine::MLS000033568::SMR000013322::cid_646130

SMILES Cn1ncc2c1ncn1c(nnc21)-c1ccccc1Cl

InChI Key InChIKey=ACXTVQMNHUMYPV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 44382   

TargetAlkaline phosphatase, tissue-nonspecific isozyme(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM44382(3-(2-Chloro-phenyl)-7-methyl-7H-pyrazolo[4,3-e][1,...)
Affinity DataIC50:  5.83E+3nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay

TargetMacrophage migration inhibitory factor(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM44382(3-(2-Chloro-phenyl)-7-methyl-7H-pyrazolo[4,3-e][1,...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of human recombinant MIF tautomerase activity using 4-hydroxyphenylpyruvate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhosphomannomutase 2(Human)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM44382(3-(2-Chloro-phenyl)-7-methyl-7H-pyrazolo[4,3-e][1,...)
Affinity DataIC50:  1.29E+4nMAssay Description:Inhibition of human purified PMM2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMannose-6-phosphate isomerase(Human)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM44382(3-(2-Chloro-phenyl)-7-methyl-7H-pyrazolo[4,3-e][1,...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of human purified phosphomannose isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed