BDBM444513 (R)-5-chloro-2-fluoro-4-(1-(3- methylbenzyl)pyrrolidin-3-ylamino)-N-(thiazol- 2-yl)benzenesulfonamide::US10662184, Example 88
SMILES Cc1cccc(c1)N1CC[C@@H](C1)Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1nccs1
InChI Key InChIKey=LSKHZCVLYTUIQZ-AWEZNQCLSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 444513
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
US Patent
Xenon Pharmaceuticals
US Patent
Affinity DataIC50: 1.25E+3nMAssay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
US Patent
Xenon Pharmaceuticals
US Patent
Affinity DataIC50: 39nMAssay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair