BDBM444517 (S)-4-(1-benzylpyrrolidin-3-yloxy)-3-chloro-N- (1,2,4-thiadiazol-5-yl)benzenesulfonamide::US10662184, Example 97

SMILES Fc1cc(O[C@H]2CCN(Cc3ccccc3)C2)c(Cl)cc1S(=O)(=O)Nc1ncns1

InChI Key InChIKey=ZLTYIRCAVATTRC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 444517   

TargetSodium channel protein type 8 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 444517BDBM444517(US10662184, Example 97 | (S)-4-(1-benzylpyrrolidin...)
Affinity DataIC50: 2.94E+3nMAssay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2021
Entry Details
US Patent