BDBM444767 US10662189, Compound WX018

SMILES CCOc1cc(ccc1OC)[C@@H](CS(C)(=O)=O)n1c2ncc(cc2[nH]c1=O)-c1ccccc1C(F)(F)F

InChI Key InChIKey=CUOCSFZLQPWEAC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 444767   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Shijiazhuang Sagacity New Drug Development

US Patent
LigandPNGBDBM444767(US10662189, Compound WX018)
Affinity DataIC50: 0.391nMAssay Description:The enzyme activity was indicated by measuring the AMP/GMP expression and tracing AMP/GMP antibody binding based on fluorescence polarization in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2021
Entry Details
US Patent