BDBM444832 6-(1-(4′-chloro-2-fluoro-5-methoxy-3′-methyl-[1,1′-biphenyl]-4-yl)-3-methylureido)-N-(isoxazol-3-yl)pyridine-3-sulfonamide::US10668067, Example 1-1

SMILES CNC(=O)N(c1ccc(cn1)S(=O)(=O)Nc1ccon1)c1cc(F)c(cc1OC)-c1ccc(Cl)c(C)c1

InChI Key InChIKey=JVQYLUACSIZAKW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 444832   

LigandChemical structure of BindingDB Monomer ID 444832BDBM444832(6-(1-(4′-chloro-2-fluoro-5-methoxy-3′-...)
Affinity DataIC50: 57nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent