BDBM444835 2-(((1r,4r)-4-(((3- fluorophenyl)(5-methylthiophen- 2-yl)carbamoyloxy)methyl) cyclohexyl)methoxy)acetic acid::US10668033, Compound 71

SMILES Cc1ccc(N(C(=O)OC[C@H]2CC[C@H](COCC(=O)O)CC2)c2cccc(F)c2)s1

InChI Key InChIKey=ONIWPUAJNWCHCD-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 444835   

TargetProstacyclin receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 444835BDBM444835(2-(((1r,4r)-4-(((3- fluorophenyl)(5-methylthiophen...)
Affinity DataEC50:  19.1nMAssay Description:Compounds were screened for agonists of the human prostacyclin (PGI2) receptor using the HTRF assay for direct cAMP measurement (Gabriel et al., ASSA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent