BDBM445013 US10668167, Compound 22

SMILES C[C@]12C[C@H](O)[C@@]3(F)[C@@H](C[C@H](F)C4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@@H](O[C@@]21C(=O)CO)c1ccc(Cc2cccc(N)c2)cc1

InChI Key InChIKey=RZCOQAQHAZHWEB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 445013   

TargetGlucocorticoid receptor(Human)
Abbvie

US Patent
LigandPNGBDBM445013(US10668167, Compound 22)
Affinity DataIC50: 8.20nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 158...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Abbvie

US Patent
LigandPNGBDBM445013(US10668167, Compound 22)
Affinity DataIC50: 28.3nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 158...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent