BDBM445024 US10668167, Compound 32

SMILES COc1cc(Cc2ccc(cc2)[C@@H]2O[C@@H]3C[C@H]4[C@@H]5C[C@H](F)C6=CC(=O)C=C[C@]6(C)[C@@]5(F)[C@@H](O)C[C@]4(C)[C@@]3(O2)C(=O)CO)ccc1N

InChI Key InChIKey=DJDDNTUYFUVZIC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 445024   

TargetGlucocorticoid receptor(Human)
Abbvie

US Patent
LigandPNGBDBM445024(US10668167, Compound 32)
Affinity DataIC50: 7.40nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 158...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetProgesterone receptor(Human)
Abbvie

US Patent
LigandPNGBDBM445024(US10668167, Compound 32)
Affinity DataIC50: 13nMAssay Description:Small molecules were tested for progersterone receptor (PR) binding using a modification of the LanthaScreen TR-FRET Progesterone Receptor Coactivato...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetAndrogen receptor(Human)
Abbvie

US Patent
LigandPNGBDBM445024(US10668167, Compound 32)
Affinity DataIC50: 3.00E+4nMAssay Description:Small molecules were tested for androgen receptor (AR) binding using a modification of the LanthaScreen TR-FRET Androgen Receptor Coactivator Assay (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetEstrogen receptor(Human)
Abbvie

US Patent
LigandPNGBDBM445024(US10668167, Compound 32)
Affinity DataIC50: 3.00E+4nMAssay Description:Small molecules were tested for estrogen receptor (ER) alpha binding using a modification of the LanthaScreen TR-FRET Estrogen Receptor Alpha Coactiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent