BDBM445051 US10668167, Compound 63

SMILES C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(cc1)S(=O)(=O)c1ccc(N)cc1

InChI Key InChIKey=HAJBHFSMKOWEHU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 445051   

TargetGlucocorticoid receptor(Human)
Abbvie

US Patent
LigandPNGBDBM445051(US10668167, Compound 63)
Affinity DataIC50: 3.80nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 158...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetProgesterone receptor(Human)
Abbvie

US Patent
LigandPNGBDBM445051(US10668167, Compound 63)
Affinity DataIC50: 447nMAssay Description:Small molecules were tested for progersterone receptor (PR) binding using a modification of the LanthaScreen TR-FRET Progesterone Receptor Coactivato...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetEstrogen receptor(Human)
Abbvie

US Patent
LigandPNGBDBM445051(US10668167, Compound 63)
Affinity DataIC50: 3.00E+4nMAssay Description:Small molecules were tested for estrogen receptor (ER) alpha binding using a modification of the LanthaScreen TR-FRET Estrogen Receptor Alpha Coactiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent