BDBM445060 US10669227, Compound 4

SMILES CNCc1ccc(\C=C\C(=O)CC(=O)\C=C\c2ccc(O)c(OC)c2)cc1

InChI Key InChIKey=GNTIMKCZICZFOB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 445060   

TargetMatrix metalloproteinase-9(Human)
The Research Foundation of State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 445060BDBM445060(US10669227, Compound 4)
Affinity DataIC50: 1.70E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetCollagenase 3(Human)
The Research Foundation of State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 445060BDBM445060(US10669227, Compound 4)
Affinity DataIC50: 2.50E+5nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

Target72 kDa type IV collagenase(Human)
The Research Foundation of State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 445060BDBM445060(US10669227, Compound 4)
Affinity DataIC50: 2.50E+5nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent