BDBM445188 (S)-1-cyano-N-(4-(3- ethylphenyl)thiazol-2-yl)- N-methylpyrrolidine-2- carboxamide::US10669234, Example 127::US11319287, Example 127

SMILES CCc1cccc(c1)-c1csc(n1)N(C)C(=O)[C@@H]1CCCN1C#N

InChI Key InChIKey=VJDMCZGYBLAWAZ-INIZCTEOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 445188   

TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Mission Therapeutics

US Patent
LigandPNGBDBM445188((S)-1-cyano-N-(4-(3- ethylphenyl)thiazol-2-yl)- N-...)
Affinity DataIC50: <100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Mission Therapeutics

US Patent
LigandPNGBDBM445188((S)-1-cyano-N-(4-(3- ethylphenyl)thiazol-2-yl)- N-...)
Affinity DataIC50: <100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent