BDBM445355 US10682352, Compound 68::Using the same manner as in Example 1, Compound 68 was obtained from Intermediate A54 and Intermediate B8.

SMILES CC(C)[C@H]1CN(C)C(=O)N1c1ccnc(N[C@@H](C)c2cn(cn2)-c2ccc(cc2)C(C)C)n1

InChI Key InChIKey=KUDKWFOWGRPOLF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 445355   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445355(Using the same manner as in Example 1, Compound 68...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
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Date in BDB:
2/15/2021
Entry Details
US Patent