BDBM445382 (4S)-4-isopropyl-1,5-methyl-3-(2-(((S)-1-(1-(4-trifluoromethylphenyl)-1H-imidazole-4-yl)ethyl)amino)pyrimidin-4-yl)imidazolidine-2-one::US10682352, Compound 95

SMILES CC(C)[C@H]1[C@H](C)N(C)C(=O)N1c1ccnc(N[C@@H](C)c2cn(cn2)-c2ccc(cc2)C(F)(F)F)n1

InChI Key InChIKey=VJYBHKVWEUMNPO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 445382   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445382((4S)-4-isopropyl-1,5-methyl-3-(2-(((S)-1-(1-(4-tri...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent