BDBM446050 US10669246, Example 101::US10968188, Example 101

SMILES F[C@H]1CC1C(=O)Nc1nc2ccc(cc2s1)-c1cnc2[nH]ccc2c1

InChI Key InChIKey=WZTMYPNAIZBREW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 446050   

TargetTyrosine-protein kinase ABL1(Human)
1St Biotherapeutics

US Patent
LigandPNGBDBM446050(US10669246, Example 101 | US10968188, Example 101)
Affinity DataIC50: 3.20nMAssay Description:c-abl kinase activity was measured by Promega's ADP-Glo Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/μl) is incubated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
1St Biotherapeutics

US Patent
LigandPNGBDBM446050(US10669246, Example 101 | US10968188, Example 101)
Affinity DataIC50: 3.20nMAssay Description:ADP-Glo assay kit was purchased from Promega. Magnesium chloride (MgCl2), bovine serum albumin (BSA), ethylene glycol-bis(β-aminoethyl ether)-N,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent