BDBM446099 2-chloro-N-{2-[4-(difluoromethyl)-1,3-thiazol-5-yl]-2-[4-(3,5- difluorophenoxy)piperidin-1-yl]ethyl}-6-fluorobenzamide::US10669267, Compound 31

SMILES FC(F)c1ncsc1C(CNC(=O)c1c(F)cccc1Cl)N1CCC(CC1)Oc1cc(F)cc(F)c1

InChI Key InChIKey=OJAGRTBSDDESFT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 446099   

TargetP2X purinoceptor 7(Rat)
Axxam

US Patent
LigandPNGBDBM446099(2-chloro-N-{2-[4-(difluoromethyl)-1,3-thiazol-5-yl...)
Affinity DataIC50: 458nMAssay Description:Ca2+ influx was measured in HEK-293 cells stably transfected with the receptor using Screen Quest Fluo-8 No Wash Calcium Assay Kit (AAt Bioquest ). B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent