BDBM446100 N-{2-[4-(difluoromethyl)-1,3-thiazol-5-yl]-2-{4-[(2- fluorophenyl)methoxy]piperidin-1-yl}ethyl}quinoline-5- carboxamide::US10669267, Compound 32

SMILES FC(F)c1ncsc1C(CNC(=O)c1cccc2ncccc12)N1CCC(CC1)OCc1ccccc1F

InChI Key InChIKey=GQRCCHLOCURSJY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 446100   

TargetP2X purinoceptor 7(Rat)
Axxam

US Patent
LigandPNGBDBM446100(N-{2-[4-(difluoromethyl)-1,3-thiazol-5-yl]-2-{4-[(...)
Affinity DataIC50: 251nMAssay Description:Ca2+ influx was measured in HEK-293 cells stably transfected with the receptor using Screen Quest Fluo-8 No Wash Calcium Assay Kit (AAt Bioquest ). B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent