BDBM446129 (3aR,6aS)-3,5-dichlorobenzyl 5-(2-oxo-2,3-::US10669268, Example 2.01

SMILES O=C(OCc1cc(Cl)cc(Cl)c1)N5CC[C@@H]4CN(C(=O)c3ccc2[nH]c(=O)oc2c3)C[C@@H]4C5

InChI Key InChIKey=ZRNBBRKTIMLWGP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 446129   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 446129BDBM446129(US10669268, Example 2.01 | (3aR,6aS)-3,5-dichlorob...)
Affinity DataIC50: 5nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent