BDBM446143 US10669268, Example 4.10::trans-3,5-dichlorobenzyl 5-(1H-benzo[d][1,2,3]triazole-5-carbonyl)hexahydro-1H-pyrrolo[3,4-c]pyridine-2(3H)-carboxylate

SMILES O=C(OCc1cc(Cl)cc(Cl)c1)N1C[C@H]2CCN(C(=O)c3ccc4[nH]nnc4c3)C[C@@H]2C1

InChI Key InChIKey=JQDSZGNVNWMBLL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 446143   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 446143BDBM446143(US10669268, Example 4.10 | trans-3,5-dichlorobenzy...)
Affinity DataIC50: 4nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent