BDBM446202 US10669268, Example 12B

SMILES O=C(OCc1cc(Cl)cc(Cl)c1)N5C[C@@H]4CCN(C(=O)c3ccc2[nH]nnc2c3)C[C@H]4C5

InChI Key InChIKey=JQDSZGNVNWMBLL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 446202   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 446202BDBM446202(US10669268, Example 12B)
Affinity DataIC50: 5nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent