BDBM446346 6-[(3aR,6aR)-2-[3-[4-::US10669268, Example 2.03

SMILES O=C(OCc1cc(Cl)cc(Cl)c1)N5CC[C@H]4CN(C(=O)c3ccc2[nH]c(=O)oc2c3)C[C@@H]4C5

InChI Key InChIKey=ZRNBBRKTIMLWGP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 446346   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 446346BDBM446346(6-[(3aR,6aR)-2-[3-[4- | US10669268, Example 2.03)
Affinity DataIC50: 5nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent