BDBM446398 CHEM-US-00328::US10669268, Example 17.17

SMILES O=C(CCc1cc(Cl)cc(C(F)(F)F)c1)N5CC[C@@H]4CN(C(=O)c3ccc2[nH]nnc2c3)C[C@@H]4CC5

InChI Key InChIKey=VFWVBZCFPJMYTJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 446398   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 446398BDBM446398(CHEM-US-00328 | US10669268, Example 17.17)
Affinity DataIC50: 4nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent