BDBM446401 CHEM-US-00331::US10669268, Example 17.20

SMILES COc1cc(CCC(=O)N2C[C@H]3CN(C(=O)c4ccc5[nH]nnc5c4)C[C@@H]3C2)cc(OC(F)(F)F)c1

InChI Key InChIKey=UHEIYZBVUJHBGO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 446401   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 446401BDBM446401(US10669268, Example 17.20)
Affinity DataIC50: 2nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent