BDBM446436 1-[(3aS,6aS)-5-[(5R)-4,5,6,7-tetrahydro-1H-benzotriazole-5-carbonyl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-2-yl]-2-[4-(trifluoromethoxy)phenoxy]ethanone::US10669268, Example 19.34

SMILES O=C(COc1ccc(OC(F)(F)F)cc1)N1C[C@@H]2CN(C(=O)[C@H]3CCc4[nH]nnc4C3)C[C@H]2C1

InChI Key InChIKey=MLFYTGBTTBULOI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 446436   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 446436BDBM446436(1-[(3aS,6aS)-5-[(5R)-4,5,6,7-tetrahydro-1H-benzotr...)
Affinity DataIC50: 3nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
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Date in BDB:
2/21/2021
Entry Details
US Patent