BDBM446482 Benzyl 2-(1,4,6,7-tetrahydrotriazolo[4,5-c]pyridine-5-carbonyl)-4,5,7,8-tetrahydropyrazolo[1,5-d][1,4]diazepine-6-carboxylate::US10669285, Example 1

SMILES O=C(OCc1ccccc1)N1CCc2cc(nn2CC1)C(=O)N1CCc2[nH]nnc2C1

InChI Key InChIKey=JZZLUZUCQVQRBW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 446482   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM446482(Benzyl 2-(1,4,6,7-tetrahydrotriazolo[4,5-c]pyridin...)
Affinity DataIC50: 158nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
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Date in BDB:
2/21/2021
Entry Details
US Patent