BDBM446484 US10669273, Compound CY-1-8::pyrido[3′,4′:4,5]pyrimido[1,2-c]indole-5,11-dione

SMILES O=C1c2ccccc2-n2c1nc1cnccc1c2=O

InChI Key InChIKey=XNPINKVTLJKOCA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 446484   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Peking University

US Patent
LigandPNGBDBM446484(pyrido[3′,4′:4,5]pyrimido[1,2-c]indole...)
Affinity DataIC50: 550nMAssay Description:Experimental method: IDO-1 can oxidatively cleave the indole ring of tryptophan to form N-formylkynurenine. Referring to the method in the literature...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Peking University

US Patent
LigandPNGBDBM446484(pyrido[3′,4′:4,5]pyrimido[1,2-c]indole...)
Affinity DataIC50: 550nMAssay Description:Experimental method: IDO-1 can oxidatively cleave the indole ring of tryptophan to form N-formylkynurenine. Referring to the method in the literature...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent