BDBM446495 9-methoxypyrido[3′,4′:4,5]pyrimido[1,2-c]indole-5,11-dione::US10669273, Compound CY-1-9

SMILES COc1ccc-2c(c1)C(=O)c1nc3cnccc3c(=O)n-21

InChI Key InChIKey=CPCDUAFPNPSADS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 446495   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Peking University

US Patent
LigandPNGBDBM446495(9-methoxypyrido[3′,4′:4,5]pyrimido[1,2...)
Affinity DataIC50: 5.50E+3nMAssay Description:Experimental method: IDO-1 can oxidatively cleave the indole ring of tryptophan to form N-formylkynurenine. Referring to the method in the literature...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent