BDBM446502 11-((2-(dimethylamino)ethoxy)imino)pyrido[2′,3′:4,5]pyrimido[1,2-α]indole-5(11H)-one::US10669273, Compound CY-1-16

SMILES CN(C)CCON=C1c2ccccc2-n2c1nc1ncccc1c2=O

InChI Key InChIKey=YREZDAHGLJYTRO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 446502   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Peking University

US Patent
LigandPNGBDBM446502(11-((2-(dimethylamino)ethoxy)imino)pyrido[2′...)
Affinity DataIC50: 550nMAssay Description:Experimental method: IDO-1 can oxidatively cleave the indole ring of tryptophan to form N-formylkynurenine. Referring to the method in the literature...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent