BDBM446508 N,N-dimethyl-2-(9-nitro-5-oxopyrido[2′,3′:4,5]pyrimido[1,2-α]indol-11(5H)-ylidene)hydrazine-1-carbothioamide::US10669273, Compound CY-1-22

SMILES CN(C)C(=S)NN=C1c2cc(ccc2-n2c1nc1ncccc1c2=O)[N+]([O-])=O

InChI Key InChIKey=UGIVPVQVIZVMMO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 446508   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Peking University

US Patent
LigandPNGBDBM446508(N,N-dimethyl-2-(9-nitro-5-oxopyrido[2′,3R...)
Affinity DataIC50: 5.5nMAssay Description:Experimental method: IDO-1 can oxidatively cleave the indole ring of tryptophan to form N-formylkynurenine. Referring to the method in the literature...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent