BDBM446512 11-(ethoxyimino)-9-nitropyrido[2′,3′:4,5]pyrimido[1,2-α]indol-5(11H)-one::US10669273, Compound CY-1-26

SMILES CCON=C1c2cc(ccc2-n2c1nc1ncccc1c2=O)[N+]([O-])=O

InChI Key InChIKey=HLONBSSUCLOXMI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 446512   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Peking University

US Patent
LigandPNGBDBM446512(11-(ethoxyimino)-9-nitropyrido[2′,3′:4...)
Affinity DataIC50: 5.50E+3nMAssay Description:Experimental method: IDO-1 can oxidatively cleave the indole ring of tryptophan to form N-formylkynurenine. Referring to the method in the literature...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent