BDBM446513 11-((allyloxy)imino)-9-nitropyrido[2′,3′:4,5]pyrimido[1,2-α]indol-5(11H)-one::US10669273, Compound CY-1-27

SMILES [O-][N+](=O)c1ccc-2c(c1)C(=NOCC=C)c1nc3ncccc3c(=O)n-21

InChI Key InChIKey=PHDZPEPEROKGIB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 446513   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Peking University

US Patent
LigandPNGBDBM446513(11-((allyloxy)imino)-9-nitropyrido[2′,3̸...)
Affinity DataIC50: 5.50E+3nMAssay Description:Experimental method: IDO-1 can oxidatively cleave the indole ring of tryptophan to form N-formylkynurenine. Referring to the method in the literature...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent