BDBM446516 2-(9-methoxy-5-oxopyrido[2′,3′:4,5]pyrimido[1,2-α]indol-11(5H)-ylidene)-N,N-di methyl-hydrazine-1-carbothioamide::US10669273, Compound CY-1-30

SMILES COc1ccc-2c(c1)C(=NNC(=S)N(C)C)c1nc3ncccc3c(=O)n-21

InChI Key InChIKey=VWZKNVZAZXUOSY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 446516   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Peking University

US Patent
LigandPNGBDBM446516(2-(9-methoxy-5-oxopyrido[2′,3′:4,5]pyr...)
Affinity DataIC50: 5.50E+3nMAssay Description:Experimental method: IDO-1 can oxidatively cleave the indole ring of tryptophan to form N-formylkynurenine. Referring to the method in the literature...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent