BDBM446517 US10669273, Compound CY-1-31::pyrido[2,3-D]pyrido[3 ‘,4’: 4,5]pyrrolo[1,2-α]pyrimidine-5,11-dione

SMILES O=C1c2cnccc2-n2c1nc1ncccc1c2=O

InChI Key InChIKey=WBKOMJIMTUCDPJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 446517   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Peking University

US Patent
LigandPNGBDBM446517(pyrido[2,3-D]pyrido[3 ‘,4’: 4,5]pyrrolo[...)
Affinity DataIC50: 5.5nMAssay Description:Experimental method: IDO-1 can oxidatively cleave the indole ring of tryptophan to form N-formylkynurenine. Referring to the method in the literature...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent