BDBM446577 4-methoxybenzyl 2-(4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridine-5-carbonyl)-7,8-dihydro-4H-pyrazolo[1,5-d][1,4]diazepine-6(5H)-carboxylate::US10669285, Example 27

SMILES COc1ccc(COC(=O)N2CCc3cc(nn3CC2)C(=O)N2CCc3[nH]nnc3C2)cc1

InChI Key InChIKey=VRACARYEVTZMOE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 446577   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM446577(4-methoxybenzyl 2-(4,5,6,7-tetrahydro-1H-[1,2,3]tr...)
Affinity DataIC50: 52nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
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Date in BDB:
2/21/2021
Entry Details
US Patent