BDBM4467 4-(4-Bromo-2-fluorophenylamino)-6,7-dimethoxyquinoline-3-carbonitrile Hydrochloride::4-[(4-bromo-2-fluorophenyl)amino]-6,7-dimethoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 30

SMILES COc1cc2ncc(C#N)c(Nc3ccc(Br)cc3F)c2cc1OC

InChI Key InChIKey=ZGDAFEZSQVKBGC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4467   

TargetEpidermal growth factor receptor(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4467(4-[(4-bromo-2-fluorophenyl)amino]-6,7-dimethoxyqui...)
Affinity DataIC50: 9.12E+4nMAssay Description:The EGF-R kinase autophosphorylation activity was measured by DELFIA/time-resolved fluorometry with excitation at 340 nm and emission at 615 nm. Po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2005
Entry Details Article
PubMed