BDBM446756 (1R,2R,3R,5R,6R)-2-amino-6-fluoro-3-(3- methylbutoxy)bicyclo[3.1.0]hexane-2,6-dicarboxylic acid::US10689327, Compound (II)-7

SMILES CC(C)CCO[C@@H]1C[C@@H]2[C@@H]([C@@]2(F)C(O)=O)[C@]1(N)C(O)=O

InChI Key InChIKey=HZLKKHXGVUNHPW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 446756   

TargetMetabotropic glutamate receptor 2(Human)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM446756((1R,2R,3R,5R,6R)-2-amino-6-fluoro-3-(3- methylbuto...)
Affinity DataIC50: 98.8nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMetabotropic glutamate receptor 3(Human)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM446756((1R,2R,3R,5R,6R)-2-amino-6-fluoro-3-(3- methylbuto...)
Affinity DataIC50: 173nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent